Vol. 2 No. 1 (2019): Current Issue
Case Report

Di George syndrome: Catch 22 (A case report)

Bector A
Department of Pediatric and Preventive Dentistry Rayat Bahra Dental College and Hospital , Mohali, Punjab, India
Dogra M
Department of Pediatric and Preventive Dentistry Rayat Bahra Dental College and Hospital , Mohali, Punjab, India
Rajpal S
Department of Pediatric and Preventive Dentistry , Rajasthan Dental College and Hospital Jaipur, India
Published March 14, 2019
Keywords
  • Digeorge,
  • Catch 22,
  • Dental caries

Abstract

The deletion of chromosome 22q11.2 is described as Velocardiofacial Syndrome orDi George Syndrome. CATCH 22 stands for cardiac defect, abnormal faces, thymichypoplasia, cleft palate, hypocalcaemia.Other defects seen are velopharyngeal insufficiency with or without cleft palate,immune problems, feeding difficulties, hypocalcaemia, learning disabilities,behavioral abnormalities and lastly characteristic facial features.A high prevalence ofdental caries, abnormalities of tooth shape, eruption and number, and enamel defectssuch as hypomineralisation and hypoplasia are also seen in these patients.A case of 7year old child with Veligocardiofacial syndrome is discussed in thisarticle. Facial dysmorphism and common dental manifestations is typically noticeablein patients with this syndrome. Enamel aberrations related to hypocalcemia mayresult in a higher frequency of dental caries. The dentists need to be aware of thedental features of this condition in order to refer them to the adequate specialists.