Poster Organic Acid Differences in Korean Obesity Feces and Anti-Obesity Effect of Formic Acid

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Myung-Ki Lee
Young Kyung Rhee


It has been reported that obesity is caused by diet and that intestinal microflora appears differently. Unlike westerners whohave a lot of meat consumption, Koreans eat more carbohydrates, less protein and lipid (the diet ratio was 60:15: 25), andalso fewer obese people (compared 4.7% of Korean to 36% of USA, BMI over 30). The purpose of this study was to investigatethe effects of dietary organic acids on obesity by analyzing organic acid metabolites in the feces of fifties aged of Korean men.In the analysis of fecal organic acids, formic acid was significantly lower in obese Koreans than in normal people, and therewas no difference in propionic acid and butyric acid, which were known as anti - obesity organic acids. In animal experimentsusing high - fat mice diet, formic acid, propionic acid and butyric acid showed anti - obesity characteristics(on body weight,cholesterol and triglyceride content, etc.). In particular, in animal experiments, formic acid significantly decreased body weight,lipid cell size, and cholesterol and triglyceride content. Although there was no difference in Korean feces, propionic acid andbutyric acid were estimated to have anti - obesity characteristics in high fat western diet because they showed anti - obesity effectin high fat mouse diet model. Therefore, it was estimated that the Korean diet induced more formic acid production, resultingin lower cholesterol and triglyceride content, suggesting that obesity is less common in Korean.

Biography:EducationB.S. Sungkyunkwan University, BiologyM.S. Sungkyunkwan University, Dairy Science (Food Microbiology)Ph.D. Sungkyunkwan University, Dairy Science (Food Microbiology)Professional Experiences1990 ~ 1992. Korea Nutrition Research Institute, Researcher1992~ present. Korea Food Research Institute, Researcher1998~1999. MacGill University, Visiting ScientistAssociation CommitteeThe Korean Society for Microbiology and Biotechnology, memberThe Korean Society of Food Science and Nutrition, member (2009, Board member)Korea Kimchi Association, Board member.


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