Journal of Nutritional Biology
Vol. 4 No. 1 (2018): Conference Proceedings: World Congress on Nutrition and Obesity Prevention Source 2017
Conference Proceedings

Oral Association Between Serum 25-Hydroxyvitamin D[25(OH)D] Levels and Depressive Symptoms in Patients Hospitalized with a Diagnosis of Depression

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  • Jong Hyun Jeong,
  • Young Eun Jung,
  • Won Myong Bahk,
  • Young Joon Kwon,
  • Bo Hyun Yoon,
  • Duk In Jon,
  • Jung Goo Lee
Jong Hyun Jeong
Department of Psychiatry, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea
Young Eun Jung
Department of Psychiatry, Jeju National University School of Medicine, Jeju, Korea
Won Myong Bahk
Department of Psychiatry, Yeouido St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea
Young Joon Kwon
Department of Psychiatry, Soonchunhyang University Cheonan Hospital, Soonchunhyang University, Cheonan, Korea
Bo Hyun Yoon
Department of Psychiatry, Naju National Hospital, Naju, Korea
Duk In Jon
Department of Psychiatry, Hallym University College of Medicine, Anyang, Korea
Jung Goo Lee
Department of Psychiatry, Haeundae Paik Hospital, College of Medicine, Inje University, Busan, Korea
Published January 1, 2018
Copyright (c) 2018 Jong Hyun Jeong

Abstract

Objectives : This study aimed to examine the association of serum 25-hydroxyvitamin D [25(OH)D] levels with the severity and dimensions of depressive symptoms in hospitalized patients with a current depressive episode. Methods : We investigated 33 patients(mean age 55.3±14.4, 81.8% women) who were hospitalized with diagnosis of depression. All participants had blood test to evaluate serum 25-hydroxyvitamin D[25(OH)D] levels on admission and were categorized to 4 groups according to their vitamin D levels. Demographic data and clinical characteristics were obtained from the structured interview by a psychiatric clinician. HAMD, HAMA, CGI and GAF were used to evaluate depressive symptoms.

Results : Normal vitamin D (>30 ng/mL), insufficiency 1(20-30 ng/mL), insufficiency 2(10-20 ng/mL), deficiency(<10 ng/ mL) were present in 15.2%, 27.3%, 42.4% and 15.2% of patients., respectively. Most of the patients(84.8%) showed the serum vitamin D levels below the normal range. There was no significant difference in demographic data and clinical characteristics between the groups. Also, there were no association between low vitamin D levels and depressive symptoms.

Conclusions : Low vitamin D levels are frequent in hospitalized patients with depression. However, in the present study, low vitamin D levels were not significantly related to the severity or clinical characteristics of depression.

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