Integrative Biomedical Sciences
Vol. 1 No. 2 (2015)
Short Communication

Detection of an Acute HIV-1 Infection Case in the Last Day of Diagnostic Window through a Combination of Two Fourth-Generation Screening Assays on a Brazilian Public Healthy Institution: We Close the Window

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  • Camila Marques de Andrade,
  • David Falango,
  • Lucas José Bazzo Menon,
  • Roberto Martinez
Camila Marques de Andrade
aboratory of Serology, Medical Support epartment, Faculty of Medicine of Ribeirao Preto, University of Sao Paulo, Sao Paulo
DOI: https://doi.org/10.18314/gjbs.v1i2.26
Published May 18, 2015

Copyright (c) 2015 Camila Marques de Andrade, David Falango, Lucas José Bazzo Menon, Roberto Martinez

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

In 2011, an estimated 2.2-2.8 million persons became infected with Human Immunodeficiency Virus (HIV) worldwide. Although the number of persons newly infected with HIV has decreased, with significant reduction in the mortality caused by the Acquired Immunodeficiency Syndrome (AIDS), the number of persons living with HIV has increased steadily. HIV-1 testing is important for limiting the spread of infection and identifying individuals who might benefit from early initiation of antiviral therapy. Diagnostic window is the time between the Human Immunodeficiency Virus (HIV) infection and laboratory diagnosis, the period during which tests for HIV are negative in infected persons. “Detecting acute infection†has also been used synonymously with “closing the windowâ€Â. We report a case where the diagnostic of acute infection was made in the last day of the diagnostic window, using a combination of two fourth-generation tests.

 

Keywords: HIV; Diagnostic window; Fourth-generation assays

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